The identification of biochanin a as a potent and selective β-site app-cleaving enzyme 1 (Bace1) inhibitor

Pharmacology, Toxicology and Pharmaceutical Science

• Beta Secretase 1 100%
• Biochanin A 71%
• Alzheimer Disease 57%
• Enzyme Kinetics 14%
• IC50 14%
• Isoflavone 14%
• Recombinant 14%
• Disease Activity 14%
• Red Clover 14%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Amyloid Precursor Protein 70%
• Enzyme Kinetics 10%
• Docking (Molecular) 10%
• IC50 10%
• Recombinant 10%
• In Vitro Study 10%
• Isoflavone 10%
• Red Clover 10%
• Binding Energy 10%
• Allosteric Site 10%

Chemistry

• % Inhibition 40%
• IC50 20%
• Red 20%
• Enzyme Kinetics 20%
• Inhibition Constant (Ki) 20%
• Binding Energy 20%
• Isoflavone 20%
• Anti Alzheimer 20%