Total synthesis of rodgersinol: A survey of the Cu(II)-mediated coupling of ortho-substituted phenols

Jong Wha Jung; Jaebong Jang; Seung Yong Seo; Jae Kyung Jung; Young Ger Suh

doi:10.1016/j.tet.2010.06.048

Total synthesis of rodgersinol: A survey of the Cu(II)-mediated coupling of ortho-substituted phenols

Jong Wha Jung, Jaebong Jang, Seung Yong Seo, Jae Kyung Jung, Young Ger Suh

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6 Scopus citations

Abstract

Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent, which avoided tedious protection/deprotection sequence.

Original language	English
Pages (from-to)	6826-6831
Number of pages	6
Journal	Tetrahedron
Volume	66
Issue number	34
DOIs	https://doi.org/10.1016/j.tet.2010.06.048
State	Published - 21 Aug 2010

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title = "Total synthesis of rodgersinol: A survey of the Cu(II)-mediated coupling of ortho-substituted phenols",

abstract = "Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent, which avoided tedious protection/deprotection sequence.",

author = "Jung, \{Jong Wha\} and Jaebong Jang and Seo, \{Seung Yong\} and Jung, \{Jae Kyung\} and Suh, \{Young Ger\}",

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T1 - Total synthesis of rodgersinol

T2 - A survey of the Cu(II)-mediated coupling of ortho-substituted phenols

AU - Jung, Jong Wha

AU - Jang, Jaebong

AU - Seo, Seung Yong

AU - Jung, Jae Kyung

AU - Suh, Young Ger

PY - 2010/8/21

Y1 - 2010/8/21

N2 - Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent, which avoided tedious protection/deprotection sequence.

AB - Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent, which avoided tedious protection/deprotection sequence.

UR - https://www.scopus.com/pages/publications/77955467770

U2 - 10.1016/j.tet.2010.06.048

DO - 10.1016/j.tet.2010.06.048

M3 - Article

AN - SCOPUS:77955467770

SN - 0040-4020

VL - 66

SP - 6826

EP - 6831

JO - Tetrahedron

JF - Tetrahedron

IS - 34

ER -

Total synthesis of rodgersinol: A survey of the Cu(II)-mediated coupling of ortho-substituted phenols

Abstract

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