Trend analysis of diabetic prevalence and incidence in a rural area of South Korea between 2003-2008

Ji Yun Jeong, Jung Guk Kim, Bo Wan Kim, Seong Su Moon, Hye Soon Kim, Keun Gyu Park, Kyu Chang Won, Hyoung Woo Lee, Ji Sung Yoon, Ho Sang Shon, Ji Hyun Lee, Eui Dal Jung, Mi Young Park, Byung Yeol Chun, Keon Yeop Kim, Tae Yoon Hwang, Mi Young Lee, In Kyu Lee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Aims/Introduction: This study determined the change in prevalence of diabetes and prediabetes over a period of 5 years in South Korea. The incidence of diabetes and prediabetes and risk factors associated with the development of diabetes were also investigated. Materials and Methods: The Dalseong population-based cohort survey recruited 1806 subjects who were over 20-years-old in 2003. Five years later, 1287 of the original subjects were re-evaluated and 187 new subjects were added to the study. All participants completed a questionnaire, were given a physical examination, and provided blood samples for analysis including 2 h oral glucose tolerances. Results: Age-adjusted prevalence of diabetes rose from 6.7% in 2003 to 9.1% in 2008. The prevalence of prediabetes also increased from 18.5% in 2003 to 28.4% in 2008. The incidence rates of diabetes and prediabetes were 18.3 per 1000 person-years and 55.4 per 1000 person-years, respectively. The development of diabetes was associated with impaired fasting glucose (IFG) (odds ratio [OR] 5.661), impaired glucose tolerance (IGT) (OR: 6.013), age (OR 1.013), and waist-to-hip ratio (OR 1.513). After excluding the IFG and IGT, systolic blood pressure (OR 1.023), high-sensitivity C-reactive protein (hsCRP; OR 1.097), triglyceride (OR 1.002) and waist-to-hip ratio (OR 1.696) were statistically significant risk factors in a multivariate logistic regression analysis. Conclusions: A significant rise in the prevalence of diabetes and prediabetes was observed between 2003 and 2008. In addition, this study newly demonstrated that waist-to-hip ratio and hsCRP were associated with the development of diabetes after adjustingv for several confounding factors.

Original languageEnglish
Pages (from-to)184-190
Number of pages7
JournalJournal of Diabetes Investigation
Volume1
Issue number5
DOIs
StatePublished - Oct 2010

Keywords

  • Diabetes mellitus
  • Prevalence
  • South Korea

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