Abstract
A new synthetic method leading to the formation of polycaprolactone (PCL)/iron oxide nanoparticles using polyvinylpyrrolidone (PVP) is described. The unique feature of this method is that the conventional polymerization step can be avoided. A stable colloidal dispersion of the PCL-coated iron oxide nanoparticles (PCLNP) is thus formed in the presence of PVP as a stabilizer. The PCLNP has a mean diameter of 20-50 nm as measured by TEM. Magnetic measurement by SQUID shows that the PCLNP has a strong superparamagnetism to be used as a liver MR T2 agent.
| Original language | English |
|---|---|
| Pages (from-to) | S19-S21 |
| Journal | Current Applied Physics |
| Volume | 9 |
| Issue number | 1 SUPPL. |
| DOIs | |
| State | Published - Jan 2009 |
Keywords
- MRI
- PCLNP
- T2 contrast agent
- USPIO