Utilization of funnel-shaped ivory flowers of Candelabra cactus for zinc oxide nanoparticles synthesis and their in-vitro anti-cancer and antibacterial activity

M. Govarthanan; P. Srinivasan; T. Selvankumar; V. Janaki; Fahad A. Al-Misned; Hamed A. El-Serehy; Woong Kim; S. Kamala-Kannan

doi:10.1016/j.matlet.2020.127951

Utilization of funnel-shaped ivory flowers of Candelabra cactus for zinc oxide nanoparticles synthesis and their in-vitro anti-cancer and antibacterial activity

M. Govarthanan, P. Srinivasan, T. Selvankumar, V. Janaki, Fahad A. Al-Misned, Hamed A. El-Serehy, Woong Kim, S. Kamala-Kannan

Department of Environmental Engineering

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The present study reports an eco-friendly phytosynthesis of zinc oxide nanoparticles (ZnONPs) using Candelabra cactus flower extract. The structural and functional properties of the synthesized ZnONPs were examined through various instrumentation. Transmission electron microscopy analysis revealed sphere-shaped ZnONPs between 10 and 30 nm in size. The synthesized ZnONPs showed growth inhibiting activity of both Gram-positive and Gram-negative bacteria. Acridine orange ethidium bromide (AO/EB) and Hoechst 33,342 staining studies revealed apoptotic bodies and chromatin condensation in the MCF-7 cancer cells.

Original language	English
Article number	127951
Journal	Materials Letters
Volume	273
DOIs	https://doi.org/10.1016/j.matlet.2020.127951
State	Published - 15 Aug 2020

Keywords

Antibacterial
Candelabra cactus
Cytotoxicity
Flower extract
MCF-7 cells

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.matlet.2020.127951

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Govarthanan, M., Srinivasan, P., Selvankumar, T., Janaki, V., Al-Misned, F. A., El-Serehy, H. A., Kim, W., & Kamala-Kannan, S. (2020). Utilization of funnel-shaped ivory flowers of Candelabra cactus for zinc oxide nanoparticles synthesis and their in-vitro anti-cancer and antibacterial activity. Materials Letters, 273, Article 127951. https://doi.org/10.1016/j.matlet.2020.127951

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title = "Utilization of funnel-shaped ivory flowers of Candelabra cactus for zinc oxide nanoparticles synthesis and their in-vitro anti-cancer and antibacterial activity",

abstract = "The present study reports an eco-friendly phytosynthesis of zinc oxide nanoparticles (ZnONPs) using Candelabra cactus flower extract. The structural and functional properties of the synthesized ZnONPs were examined through various instrumentation. Transmission electron microscopy analysis revealed sphere-shaped ZnONPs between 10 and 30 nm in size. The synthesized ZnONPs showed growth inhibiting activity of both Gram-positive and Gram-negative bacteria. Acridine orange ethidium bromide (AO/EB) and Hoechst 33,342 staining studies revealed apoptotic bodies and chromatin condensation in the MCF-7 cancer cells.",

keywords = "Antibacterial, Candelabra cactus, Cytotoxicity, Flower extract, MCF-7 cells",

author = "M. Govarthanan and P. Srinivasan and T. Selvankumar and V. Janaki and Al-Misned, {Fahad A.} and El-Serehy, {Hamed A.} and Woong Kim and S. Kamala-Kannan",

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doi = "10.1016/j.matlet.2020.127951",

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AU - Govarthanan, M.

AU - Srinivasan, P.

AU - Selvankumar, T.

AU - Janaki, V.

AU - Al-Misned, Fahad A.

AU - El-Serehy, Hamed A.

AU - Kim, Woong

AU - Kamala-Kannan, S.

PY - 2020/8/15

Y1 - 2020/8/15

N2 - The present study reports an eco-friendly phytosynthesis of zinc oxide nanoparticles (ZnONPs) using Candelabra cactus flower extract. The structural and functional properties of the synthesized ZnONPs were examined through various instrumentation. Transmission electron microscopy analysis revealed sphere-shaped ZnONPs between 10 and 30 nm in size. The synthesized ZnONPs showed growth inhibiting activity of both Gram-positive and Gram-negative bacteria. Acridine orange ethidium bromide (AO/EB) and Hoechst 33,342 staining studies revealed apoptotic bodies and chromatin condensation in the MCF-7 cancer cells.

AB - The present study reports an eco-friendly phytosynthesis of zinc oxide nanoparticles (ZnONPs) using Candelabra cactus flower extract. The structural and functional properties of the synthesized ZnONPs were examined through various instrumentation. Transmission electron microscopy analysis revealed sphere-shaped ZnONPs between 10 and 30 nm in size. The synthesized ZnONPs showed growth inhibiting activity of both Gram-positive and Gram-negative bacteria. Acridine orange ethidium bromide (AO/EB) and Hoechst 33,342 staining studies revealed apoptotic bodies and chromatin condensation in the MCF-7 cancer cells.

KW - Antibacterial

KW - Candelabra cactus

KW - Cytotoxicity

KW - Flower extract

KW - MCF-7 cells

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DO - 10.1016/j.matlet.2020.127951

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VL - 273

JO - Materials Letters

JF - Materials Letters

M1 - 127951

ER -

Utilization of funnel-shaped ivory flowers of Candelabra cactus for zinc oxide nanoparticles synthesis and their in-vitro anti-cancer and antibacterial activity

Abstract

Keywords

UN SDGs

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