TY - JOUR
T1 - Validation of the Bipolar Prodrome Symptom Interview and Scale-Abbreviated Prospective (BPSS-AP) in a clinical sample and healthy controls
AU - Lee, Junhee
AU - Correll, Christoph U.
AU - Lee, Tae Young
AU - Oh, Sanghoon
AU - Kim, Jayoun
AU - Rhee, Sang Jin
AU - Kim, Minah
AU - Kim, Se Hyun
AU - Ahn, Yong Min
AU - Ha, Kyooseob
AU - Kwon, Jun Soo
N1 - Publisher Copyright:
© 2022 Elsevier B.V.
PY - 2023/3/1
Y1 - 2023/3/1
N2 - Background: After the existence of a bipolar disorder (BD) prodrome was established, the development of clinical rating instruments has become relevant that are sufficiently brief to be implemented in real-world clinical practice and that are designed to identify individuals at-risk for BD. This study aimed to validate a shorter version of the Bipolar Prodrome Symptom Interview and Scale (BPSS), the BPSS-Abbreviated Prospective (BPSS-AP), for use among clinical populations. Methods: Altogether, 104 adults, comprising individuals diagnosed with BD (n = 17, mania: n = 8, hypomania: n = 9), with major depressive disorder (MDD, n = 38, all currently depressed), and healthy controls (HCs, n = 49), underwent BPSS-AP interviews. The psychometric properties of the BPSS-AP were evaluated, including internal consistency, convergent validity, discriminant validity, and factor structure. Results: The median (IQR) age was 29 (23–38), 40 (23–55), and 25 (22–28) years, for the BD, MDD, and HC groups, respectively. The BPSS-AP showed excellent internal consistency (Cronbach's α = 0.95). Convergent validity between the BPSS-AP and Young Mania Rating Scale (YMRS) was high (r > 0.7). The BPSS-AP discriminated patients with BD from those with MDD (P <.001) and from HCs (P <.001). Limitations: The study design precludes assessment of the predictive validity of the BPSS-AP. Conclusions: This study found that the BPSS-AP, a more concise and feasible version of the semi-structured interview for identifying individuals at risk of developing BD, has satisfactory psychometric properties. There is room for further validation and application of the BPSS-AP in clinical settings to evaluate its utility in research and clinical care.
AB - Background: After the existence of a bipolar disorder (BD) prodrome was established, the development of clinical rating instruments has become relevant that are sufficiently brief to be implemented in real-world clinical practice and that are designed to identify individuals at-risk for BD. This study aimed to validate a shorter version of the Bipolar Prodrome Symptom Interview and Scale (BPSS), the BPSS-Abbreviated Prospective (BPSS-AP), for use among clinical populations. Methods: Altogether, 104 adults, comprising individuals diagnosed with BD (n = 17, mania: n = 8, hypomania: n = 9), with major depressive disorder (MDD, n = 38, all currently depressed), and healthy controls (HCs, n = 49), underwent BPSS-AP interviews. The psychometric properties of the BPSS-AP were evaluated, including internal consistency, convergent validity, discriminant validity, and factor structure. Results: The median (IQR) age was 29 (23–38), 40 (23–55), and 25 (22–28) years, for the BD, MDD, and HC groups, respectively. The BPSS-AP showed excellent internal consistency (Cronbach's α = 0.95). Convergent validity between the BPSS-AP and Young Mania Rating Scale (YMRS) was high (r > 0.7). The BPSS-AP discriminated patients with BD from those with MDD (P <.001) and from HCs (P <.001). Limitations: The study design precludes assessment of the predictive validity of the BPSS-AP. Conclusions: This study found that the BPSS-AP, a more concise and feasible version of the semi-structured interview for identifying individuals at risk of developing BD, has satisfactory psychometric properties. There is room for further validation and application of the BPSS-AP in clinical settings to evaluate its utility in research and clinical care.
KW - Bipolar disorder
KW - Prodromal symptoms
KW - Psychiatric status rating scales
UR - http://www.scopus.com/inward/record.url?scp=85145829858&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2022.12.115
DO - 10.1016/j.jad.2022.12.115
M3 - Article
C2 - 36586622
AN - SCOPUS:85145829858
SN - 0165-0327
VL - 324
SP - 463
EP - 468
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -