Water-soluble Ultra Small paramagnetic or superparamagnetic metal oxide nanoparticles for molecular MR imaging

Ja Young Park, Eun Sook Choi, Myung Ju Baek, Gang Ho Lee, Seungtae Woo, Yongmin Chang

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

A simple and general one-pot synthesis for water-soluble ligand-coated ultra small paramagnetic or superparamagnetic metal oxide nanoparticles with average particle diameters (dav.) that range from. 1-3 run has been developed and used in molecular magnetic resonance (MR) imaging. The iron oxide, manganese oxide, and gadolinium oxide nanoparticles are coated with various hydrophilic and biocompatible ligands. We found that the ligand-coated ultra small gadolinium oxide nanoparticles are the superior candidates for use as T1 MRI contrast agents.

Original languageEnglish
Pages (from-to)2477-2481
Number of pages5
JournalEuropean Journal of Inorganic Chemistry
Issue number17
DOIs
StatePublished - Jun 2009

Keywords

  • Colloids
  • Imaging agents
  • Nanostructures
  • Nanotechnology

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